Cyclohexenyl nucleosides: Synthesis of cis-4-(9H-purin-9-yl)-2-cyclohexenylcarbinols

Michael J. Konkel, Robert Vince

Research output: Contribution to journalArticlepeer-review

42 Scopus citations

Abstract

Syntheses of the title compounds were accomplished in 6-7 steps, starting from cyclohexadiene and chlorosulphonyl isocyanate. The key step of the strategy involves a palladium coupling of cyclohexenyl dicarbonate 8 with either 6-chloropurine or 2-amino-6-chloropurine.

Original languageEnglish (US)
Pages (from-to)799-808
Number of pages10
JournalTetrahedron
Volume52
Issue number3
DOIs
StatePublished - Jan 15 1996

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