Cycloadditions of noncomplementary substituted 1,2,3-triazines

Erin D. Anderson, Adam S. Duerfeldt, Kaicheng Zhu, Christopher M. Glinkerman, Dale L. Boger

Research output: Contribution to journalArticlepeer-review

49 Scopus citations


The scope of the [4 + 2] cycloaddition reactions of substituted 1,2,3-triazines, bearing noncomplementary substitution with electron-withdrawing groups at C4 and/or C6, is described. The studies define key electronic and steric effects of substituents impacting the reactivity, mode (C4/N1 vs C5/N2), and regioselectivity of the cycloaddition reactions of 1,2,3-triazines with amidines, enamines, and ynamines, providing access to highly functionalized heterocycles.

Original languageEnglish (US)
Pages (from-to)5084-5087
Number of pages4
JournalOrganic Letters
Issue number19
StatePublished - Oct 3 2014
Externally publishedYes

Bibliographical note

Publisher Copyright:
© 2014 American Chemical Society.


Dive into the research topics of 'Cycloadditions of noncomplementary substituted 1,2,3-triazines'. Together they form a unique fingerprint.

Cite this