Cyclic strain induces dual-mode endothelialmesenchymal transformation of the cardiac valve

Keyphrases

• Dual-mode 100%
• Cardiac Valves 100%
• Cyclic Strain 100%
• Endothelial-to-mesenchymal Transformation 100%
• Valve Tissue 27%
• Catenin 18%
• Endothelium 18%
• TGF-1 18%
• High Strain 18%
• Tissue Microenvironment 9%
• Regulatory Role 9%
• Sheep 9%
• Mammary Tumor 9%
• Spatiotemporal 9%
• Functional Properties 9%
• Mechanical Strain 9%
• Microenvironment 9%
• Anisotropy 9%
• Inducer 9%
• Microarchitecture 9%
• Endothelin-1 (ET-1) 9%
• Contractility 9%
• Mitogen 9%
• Embryonic Morphogenesis 9%
• Strain-dependent 9%
• Integration Site 9%
• Valve Leaflet 9%
• Strain Magnitude 9%
• Isotropy 9%
• Low Strain 9%
• Virus Integration 9%
• Microcontact Printing 9%
• Tumor Virus 9%
• Cyclic Mechanical Strain 9%
• Valvulogenesis 9%
• Valve Endothelial Cells 9%
• 2D Valve 9%

Biochemistry, Genetics and Molecular Biology

• Catenin 100%
• Anisotropy 50%
• Morphogenesis 50%
• Mouse Mammary Tumor Virus 50%
• Muscle Contractility 50%
• Virus DNA Cell DNA Interaction 50%
• Vascular Endothelial Growth Factor 50%
• Endothelin 1 50%

Engineering

• Cyclic Strain 100%
• Mesenchymal Transformation 100%
• Dual-Mode 100%
• Microenvironments 18%
• Engineered Valve 18%
• Mechanical Strain 18%
• Disruptions 9%
• Dependent Strain 9%
• Leaflet Valve 9%
• Dependent Manner 9%
• Critical Event 9%
• Functional Property 9%
• Microcontact Printing 9%
• Spatial Distribution 9%