Allergic fungal rhinosinusitis (AFRS) represents a subtype of chronic rhinosinusitis with nasal polyposis that exhibits a unique, often striking clinical presentation. Since its initial description more than a quarter century ago, a more sophisticated understanding of the pathophysiology of AFRS has been achieved and significant advancements in improving clinical outcomes made. This review focuses on the latest developments involving the pathophysiology and clinical management of this fascinating disease.
Bibliographical noteFunding Information:
A.U. Luong serves as a consultant for Aerin Medical (Sunnyvale, California), Arrinex (Redwood City, California), Lyra Therapeutics (Watertown, Massachusetts), and Stryker (Kalamazoo, Michigan). She is on the advisory board for ENTvantage (Austin, Texas), Sanofi (Paris, France), and Novartis (Basel, Switzerland).
© 2019 Elsevier Inc.
- Allergic fungal rhinosinusitis
- Allergic sinusitis
- Chronic rhinosinusitis
- Eosinophilic mucin rhinosinusitis
- Fungal allergy
- Fungal sinusitis
- Nasal polyps
- Type 2 inflammation