Current Concepts in the Management of Allergic Fungal Rhinosinusitis

Matthew A. Tyler, Amber U. Luong

Research output: Contribution to journalReview articlepeer-review

11 Scopus citations


Allergic fungal rhinosinusitis (AFRS) represents a subtype of chronic rhinosinusitis with nasal polyposis that exhibits a unique, often striking clinical presentation. Since its initial description more than a quarter century ago, a more sophisticated understanding of the pathophysiology of AFRS has been achieved and significant advancements in improving clinical outcomes made. This review focuses on the latest developments involving the pathophysiology and clinical management of this fascinating disease.

Original languageEnglish (US)
Pages (from-to)345-359
Number of pages15
JournalImmunology and Allergy Clinics of North America
Issue number2
StatePublished - May 2020

Bibliographical note

Funding Information:
A.U. Luong serves as a consultant for Aerin Medical (Sunnyvale, California), Arrinex (Redwood City, California), Lyra Therapeutics (Watertown, Massachusetts), and Stryker (Kalamazoo, Michigan). She is on the advisory board for ENTvantage (Austin, Texas), Sanofi (Paris, France), and Novartis (Basel, Switzerland).

Publisher Copyright:
© 2019 Elsevier Inc.


  • Allergic fungal rhinosinusitis
  • Allergic sinusitis
  • Chronic rhinosinusitis
  • Eosinophilic mucin rhinosinusitis
  • Fungal allergy
  • Fungal sinusitis
  • Nasal polyps
  • Type 2 inflammation

PubMed: MeSH publication types

  • Journal Article
  • Review


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