Current and Future Directions of Research on Stress and Addictive Behaviors

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations


This book includes the latest discoveries on the interactions of stress neurobiology and addiction. It addresses the role of stress in addiction vulnerability, maintenance, and relapse from basic and clinical perspectives. This chapter highlights some of these discoveries and relates them to conceptual framework linking stress and addiction processes. There is compelling evidence of the importance of considering stress when addressing addiction vulnerability and tackling issues related to treatment and recovery. The chapter discusses in detail components of a multivariate working model, focusing first on the role of stress in addiction vulnerability and the physiological mechanisms mediating this risk. It then highlights the role of stress in maintaining addiction and in precipitating relapse. Next, it highlights issues that moderate the interaction of stress and addiction, including genetics, sex, and coping style. It briefly discusses how impulsivity and cognitive deficits may mediate the effects of stress on addiction processes. Finally, the chapter outlines a research agenda for the future that builds on the current state of knowledge and advances it toward more discoveries to improve diagnosis and treatment of addictions.

Original languageEnglish (US)
Title of host publicationStress and Addiction
Subtitle of host publicationBiological and Psychological Mechanisms
Number of pages23
ISBN (Print)9780123706324
StatePublished - Dec 22 2006

Bibliographical note

Publisher Copyright:
© 2007 Elsevier Inc. All rights reserved.


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