Crystallization of ADP-ribosyl cyclase from Aplysia californica

G. Sridhar Prasad, David G Levitt, Hon Cheung Lee, Charles D. Stout

Research output: Contribution to journalArticlepeer-review

16 Scopus citations

Abstract

ADP-ribosyl cyclase synthesizes the secondary messenger cyclic ADP-ribose from NAD+. Diffraction quality crystals of the enzyme from ovotestes of Aplysia californica have been obtained. Crystallographic analysis of this enzyme will yield insight into the mode of binding of the novel cyclic nucleotide and the mechanism by which NAD+ is cyclized.

Original languageEnglish (US)
Pages (from-to)138-140
Number of pages3
JournalProteins: Structure, Function and Genetics
Volume24
Issue number1
DOIs
StatePublished - 1996

Keywords

  • ADP-ribosyl cyclase
  • crystals

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