Cryptococcal meningitis with false-positive cytology in the CSF. Use of T-cell rosetting to exclude meningeal lymphoma

Scott F Davies, B. J. Gormus, R. Yarchoan, M. E. Kaplan

Research output: Contribution to journalArticlepeer-review

22 Scopus citations

Abstract

Cryptococcal meningitis is a frequently described complication of malignant lymphoma. A patient with nodular, poorly differentiated lymphocytic lymphoma (a B-cell neoplasm) had a notable alteration in mental status. Examination of the CSF showed characteristic cryptococcal organisms, but also was believed to demonstrate CNS involvement with lymphoma. A T-cell rosetting assay proved clinically useful by identifying the atypical lymphocytes as T cells rather than neoplastic B cells.

Original languageEnglish (US)
Pages (from-to)2369-2370
Number of pages2
JournalJournal of the American Medical Association
Volume239
Issue number22
DOIs
StatePublished - Dec 1 1978

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