Cross-sectional study of sex differences in psychosocial quality of life of long-term melanoma survivors

Rachel I. Vogel; Broderick Yoerg; Patricia I. Jewett; Nathan Rubin; Megan Olson; Ashley E. Stenzel; Rehana L. Ahmed; De Ann Lazovich

doi:10.1007/s00520-021-06046-7

Cross-sectional study of sex differences in psychosocial quality of life of long-term melanoma survivors

Rachel I. Vogel, Broderick Yoerg, Patricia I. Jewett, Nathan Rubin, Megan Olson, Ashley E. Stenzel, Rehana L. Ahmed, De Ann Lazovich

Research output: Contribution to journal › Article › peer-review

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Abstract

PURPOSE: A cancer diagnosis and subsequent treatment can have a significant impact on an individual's quality of life. Differences in quality of life by sex among long-term melanoma survivors remain unclear. The objective of this study was to describe sex differences in cancer-specific psychosocial quality of life of long-term melanoma survivors.

METHODS: Melanoma survivors 7-10 years post-diagnosis from a previously conducted population-based case-control study were recruited for a cross-sectional survey. Validated measures of psychosocial quality of life related to melanoma diagnosis were assessed. Outcomes were compared by sex using linear regression models adjusting for age, education, income, and marital status.

RESULTS: The survey response rate was 62% (433 females, 291 males; 86% stage I disease). Females were more likely to report changes in their appearance (p = 0.006) and being more fearful of recurrence (p = 0.001) or a second melanoma (p = 0.001) than males but were also more likely to report that melanoma had a positive impact on their lives (p < 0.0001). Males were more likely to agree with statements that emphasized that life's duration is limited (p < 0.0001).

CONCLUSION: Long-term melanoma survivors reported generally favorable measures of psychosocial quality of life related to their diagnosis. Females and males reported unique quality of life concerns and may require varied methods of support following a melanoma diagnosis.

Original language	English (US)
Pages (from-to)	5663-5671
Number of pages	9
Journal	Supportive Care in Cancer
Volume	29
Issue number	10
Early online date	Feb 12 2021
DOIs	https://doi.org/10.1007/s00520-021-06046-7
State	Published - Oct 2021

Bibliographical note

Funding Information:
This work was supported by a grant from the Masonic Cancer Center of the University of Minnesota’s internal grants program (Lazovich), National Cancer Institute, National Institutes of Health, grant P30 CA77598 (PI: Yee) utilizing the Biostatistics Core, a shared resource of the Masonic Cancer Center (Vogel), and National Center for Advancing Translational Sciences of the National Institutes of Health grant UL1TR002494 (PI: Blazar) for utilization of REDCap (Vogel). Work on this manuscript was additionally supported by the Wayne Stinchcomb Big Orange Foundation-Melanoma Research Alliance Young Investigator Award (Vogel) and National Cancer Institute, National Institutes of Health grant T32CA163184 (Stenzel). The funders had no role in the design of the study and collection, analysis, or interpretation of data and in writing the manuscript.

Publisher Copyright:
© 2021, The Author(s), under exclusive licence to Springer-Verlag GmbH, DE part of Springer Nature.

Keywords

Cancer survivorship
Melanoma
Quality of life
Sex differences

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1007/s00520-021-06046-7

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title = "Cross-sectional study of sex differences in psychosocial quality of life of long-term melanoma survivors",

abstract = "PURPOSE: A cancer diagnosis and subsequent treatment can have a significant impact on an individual's quality of life. Differences in quality of life by sex among long-term melanoma survivors remain unclear. The objective of this study was to describe sex differences in cancer-specific psychosocial quality of life of long-term melanoma survivors.METHODS: Melanoma survivors 7-10 years post-diagnosis from a previously conducted population-based case-control study were recruited for a cross-sectional survey. Validated measures of psychosocial quality of life related to melanoma diagnosis were assessed. Outcomes were compared by sex using linear regression models adjusting for age, education, income, and marital status.RESULTS: The survey response rate was 62% (433 females, 291 males; 86% stage I disease). Females were more likely to report changes in their appearance (p = 0.006) and being more fearful of recurrence (p = 0.001) or a second melanoma (p = 0.001) than males but were also more likely to report that melanoma had a positive impact on their lives (p < 0.0001). Males were more likely to agree with statements that emphasized that life's duration is limited (p < 0.0001).CONCLUSION: Long-term melanoma survivors reported generally favorable measures of psychosocial quality of life related to their diagnosis. Females and males reported unique quality of life concerns and may require varied methods of support following a melanoma diagnosis.",

keywords = "Cancer survivorship, Melanoma, Quality of life, Sex differences",

author = "Vogel, {Rachel I.} and Broderick Yoerg and Jewett, {Patricia I.} and Nathan Rubin and Megan Olson and Stenzel, {Ashley E.} and Ahmed, {Rehana L.} and Lazovich, {De Ann}",

note = "Funding Information: This work was supported by a grant from the Masonic Cancer Center of the University of Minnesota{\textquoteright}s internal grants program (Lazovich), National Cancer Institute, National Institutes of Health, grant P30 CA77598 (PI: Yee) utilizing the Biostatistics Core, a shared resource of the Masonic Cancer Center (Vogel), and National Center for Advancing Translational Sciences of the National Institutes of Health grant UL1TR002494 (PI: Blazar) for utilization of REDCap (Vogel). Work on this manuscript was additionally supported by the Wayne Stinchcomb Big Orange Foundation-Melanoma Research Alliance Young Investigator Award (Vogel) and National Cancer Institute, National Institutes of Health grant T32CA163184 (Stenzel). The funders had no role in the design of the study and collection, analysis, or interpretation of data and in writing the manuscript. Publisher Copyright: {\textcopyright} 2021, The Author(s), under exclusive licence to Springer-Verlag GmbH, DE part of Springer Nature.",

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T1 - Cross-sectional study of sex differences in psychosocial quality of life of long-term melanoma survivors

AU - Vogel, Rachel I.

AU - Yoerg, Broderick

AU - Jewett, Patricia I.

AU - Rubin, Nathan

AU - Olson, Megan

AU - Stenzel, Ashley E.

AU - Ahmed, Rehana L.

AU - Lazovich, De Ann

N1 - Funding Information: This work was supported by a grant from the Masonic Cancer Center of the University of Minnesota’s internal grants program (Lazovich), National Cancer Institute, National Institutes of Health, grant P30 CA77598 (PI: Yee) utilizing the Biostatistics Core, a shared resource of the Masonic Cancer Center (Vogel), and National Center for Advancing Translational Sciences of the National Institutes of Health grant UL1TR002494 (PI: Blazar) for utilization of REDCap (Vogel). Work on this manuscript was additionally supported by the Wayne Stinchcomb Big Orange Foundation-Melanoma Research Alliance Young Investigator Award (Vogel) and National Cancer Institute, National Institutes of Health grant T32CA163184 (Stenzel). The funders had no role in the design of the study and collection, analysis, or interpretation of data and in writing the manuscript. Publisher Copyright: © 2021, The Author(s), under exclusive licence to Springer-Verlag GmbH, DE part of Springer Nature.

PY - 2021/10

Y1 - 2021/10

N2 - PURPOSE: A cancer diagnosis and subsequent treatment can have a significant impact on an individual's quality of life. Differences in quality of life by sex among long-term melanoma survivors remain unclear. The objective of this study was to describe sex differences in cancer-specific psychosocial quality of life of long-term melanoma survivors.METHODS: Melanoma survivors 7-10 years post-diagnosis from a previously conducted population-based case-control study were recruited for a cross-sectional survey. Validated measures of psychosocial quality of life related to melanoma diagnosis were assessed. Outcomes were compared by sex using linear regression models adjusting for age, education, income, and marital status.RESULTS: The survey response rate was 62% (433 females, 291 males; 86% stage I disease). Females were more likely to report changes in their appearance (p = 0.006) and being more fearful of recurrence (p = 0.001) or a second melanoma (p = 0.001) than males but were also more likely to report that melanoma had a positive impact on their lives (p < 0.0001). Males were more likely to agree with statements that emphasized that life's duration is limited (p < 0.0001).CONCLUSION: Long-term melanoma survivors reported generally favorable measures of psychosocial quality of life related to their diagnosis. Females and males reported unique quality of life concerns and may require varied methods of support following a melanoma diagnosis.

AB - PURPOSE: A cancer diagnosis and subsequent treatment can have a significant impact on an individual's quality of life. Differences in quality of life by sex among long-term melanoma survivors remain unclear. The objective of this study was to describe sex differences in cancer-specific psychosocial quality of life of long-term melanoma survivors.METHODS: Melanoma survivors 7-10 years post-diagnosis from a previously conducted population-based case-control study were recruited for a cross-sectional survey. Validated measures of psychosocial quality of life related to melanoma diagnosis were assessed. Outcomes were compared by sex using linear regression models adjusting for age, education, income, and marital status.RESULTS: The survey response rate was 62% (433 females, 291 males; 86% stage I disease). Females were more likely to report changes in their appearance (p = 0.006) and being more fearful of recurrence (p = 0.001) or a second melanoma (p = 0.001) than males but were also more likely to report that melanoma had a positive impact on their lives (p < 0.0001). Males were more likely to agree with statements that emphasized that life's duration is limited (p < 0.0001).CONCLUSION: Long-term melanoma survivors reported generally favorable measures of psychosocial quality of life related to their diagnosis. Females and males reported unique quality of life concerns and may require varied methods of support following a melanoma diagnosis.

KW - Cancer survivorship

KW - Melanoma

KW - Quality of life

KW - Sex differences

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Cross-sectional study of sex differences in psychosocial quality of life of long-term melanoma survivors

Abstract

Bibliographical note

Keywords

UN SDGs

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