Critical role of substrate conformational change in the proton transfer process catalyzed by 4-oxalocrotonate tautomerase

Keyphrases

• Proton Transfer 100%
• Conformational Change 100%
• Proton Transfer Mechanism 100%
• 4-Oxalocrotonate tautomerase 100%
• Isomerization 50%
• Enzyme Catalysis 25%
• Quantum Mechanical 25%
• Canonical Variational Transition State Theory 25%
• Mechanical Method 25%
• Chemical Processes 25%
• Density Functional 25%
• Proline 25%
• Vibrational Motion 25%
• Active Sites 25%
• Nitrogen Atom 25%
• Potential Energy Surface 25%
• Transition State 25%
• Reaction Progress 25%
• Reaction Coordinate 25%
• Dual-level 25%
• Multidimensional Tunneling 25%
• Transmission Coefficient 25%
• Electron Distribution 25%
• Intermediate State 25%
• Deprotonated 25%
• Overall Process 25%
• Free Energy Barrier 25%
• Primary Zone 25%
• Stable Intermediate 25%
• Quantum Subsystem 25%

Chemistry

• Proton Transfer 100%
• Transfer Process 100%
• Isomerization 40%
• Statistical Ensemble 40%
• Hexenedioate 40%
• Transition State Theory 20%
• Energy Barrier 20%
• Nitrogen Atom 20%
• Potential Energy Surface 20%
• Transition State 20%
• Rate Constant 20%
• Corresponding State 20%
• Electron Configuration 20%
• Proline 20%
• Free Energy 20%

Biochemistry, Genetics and Molecular Biology

• Conformational Change 100%
• Proton Transport 100%
• Isomerization 40%
• Active Site 20%
• Motion 20%
• Enzyme Catalysis 20%
• Chemical Reaction 20%
• Proline 20%