Critical review: Typical and atypical optic neuritis

Research output: Contribution to journalReview articlepeer-review

69 Scopus citations


Typical optic neuritis is an idiopathic demyelinating condition that is often associated with multiple sclerosis. This has been well characterized and has an excellent prognosis. Atypical optic neuritis can result from an inflammatory, infectious, or autoimmune disorder. Differentiating the two types of optic neuritis is paramount and may be challenging early on in the clinical course. This review describes the recent literature describing the pathophysiology, clinical presentation, neuroimaging, and management of these disorders.

Original languageEnglish (US)
Pages (from-to)770-779
Number of pages10
JournalSurvey of Ophthalmology
Issue number6
StatePublished - Jun 24 2019


  • infectious optic neuritis
  • inflammatory optic neuritis
  • multiple sclerosis
  • myelin oligodendrocyte glycoprotein antibody
  • neuromyelitis optica
  • optic neuritis
  • optic perineuritis

PubMed: MeSH publication types

  • Journal Article
  • Review


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