Creation of an intra-atrial communication with a new Amplatzer shunt prosthesis: Preliminary results in a swine model

Huafu Kong, Xiaoping Gu, Jack L. Titus, Tae Hoon Kim, Myra Urness, Young Min Han, Peter Hessliein, John L Bass, Meelee Chun, David W. Hunter

Research output: Contribution to journalArticlepeer-review

9 Scopus citations

Abstract

A nitinol shunt device was applied in six minipigs to create a precise intra-atrial shunt. This self-expanding shunt device consists of two retention disks of 2-8 mm, a 4 mm connecting waist with a 10 mm eccentric hole. It requires a 7 Fr introducer sheath. The device is attached to the delivery cable with a microscrew. Placement technique is identical to that of Amplatzer septal occluder. Balloon dilation was performed immediately and 1 month after placement. One animal died from general anesthesia before device placement. Left atrial angiography showed a patent intra-atrial shunt in 5/5 pigs immediately and 4/4 in 1- to 3-month follow up. Postmortem examination demonstrated patent shunts partially or completely neoendothelialized. The shunt device was found to be an effective and safe way to create a permanent atrial communication.

Original languageEnglish (US)
Pages (from-to)267-271
Number of pages5
JournalCatheterization and Cardiovascular Interventions
Volume56
Issue number2
DOIs
StatePublished - Jun 8 2002

Keywords

  • Atrial septostomy
  • Congenital heart disease
  • Shunt
  • Stent

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