Personalized learning environments and learning analytics hold the promise to transform learning experiences, enhance and accelerate student success, and "open up" student learning to resources and experiences from outside individual institutions. To achieve their potential, personalized learning projects must move beyond individual, stand-alone projects or innovations to reshaping the institutional experience. Learning science must connect with learning pedagogy and design. Learners and institutions must have access to tools and resources that assist in customizing student progress and supplemental learning needs. Teachers and faculty must be empowered to provide teaching and learning environments that allow individual students to thrive. All this will require unique partnerships and collaborations within and across institutions, incorporating the best learning science findings and bridging with public and private entities developing the learning and analytic tools to support personalized learning. Crafting a strategy to embrace and sustain the transformative power of personalized learning systems will require strong leadership and clear planning models to align with institutional planning and future investments.