Cortical atrophy in young adults with a history of hyperactivity in childhood

Henry A. Nasrallah; Jan Loney; Stephen C. Olson; Mona McCalley-Whitters; John Kramer; Charles G. Jacoby

doi:10.1016/0165-1781(86)90052-1

Cortical atrophy in young adults with a history of hyperactivity in childhood

Henry A. Nasrallah
, Jan Loney
, Stephen C. Olson
, Mona McCalley-Whitters
, John Kramer
, Charles G. Jacoby

Psychiatry & Behavioral Sciences

Research output: Contribution to journal › Article › peer-review

45 Scopus citations

Abstract

A computed tomographic (CT) brain scan study was conducted in 24 young males treated and followed up for hyperactivity since childhood. Compared to 27 matched controls, adults with a history of hyperactivity had a significantly greater frequency of cerebral atrophy. No differences in cerebellar atrophy frequency or in lateral cerebral ventricle-to-brain ratio (VBR) were found. The possible associations of hyperactivity or perhaps stimulant drug treatment to atrophic brain changes are discussed.

Original language	English (US)
Pages (from-to)	241-246
Number of pages	6
Journal	Psychiatry Research
Volume	17
Issue number	3
DOIs	https://doi.org/10.1016/0165-1781(86)90052-1
State	Published - Mar 1986

Keywords

Computerized tomography
cerebellar atrophy
cortical atrophy
hyperactivity
ventricular enlargment

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10.1016/0165-1781(86)90052-1

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title = "Cortical atrophy in young adults with a history of hyperactivity in childhood",

abstract = "A computed tomographic (CT) brain scan study was conducted in 24 young males treated and followed up for hyperactivity since childhood. Compared to 27 matched controls, adults with a history of hyperactivity had a significantly greater frequency of cerebral atrophy. No differences in cerebellar atrophy frequency or in lateral cerebral ventricle-to-brain ratio (VBR) were found. The possible associations of hyperactivity or perhaps stimulant drug treatment to atrophic brain changes are discussed.",

keywords = "Computerized tomography, cerebellar atrophy, cortical atrophy, hyperactivity, ventricular enlargment",

author = "Nasrallah, \{Henry A.\} and Jan Loney and Olson, \{Stephen C.\} and Mona McCalley-Whitters and John Kramer and Jacoby, \{Charles G.\}",

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language = "English (US)",

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T1 - Cortical atrophy in young adults with a history of hyperactivity in childhood

AU - Nasrallah, Henry A.

AU - Loney, Jan

AU - Olson, Stephen C.

AU - McCalley-Whitters, Mona

AU - Kramer, John

AU - Jacoby, Charles G.

PY - 1986/3

Y1 - 1986/3

N2 - A computed tomographic (CT) brain scan study was conducted in 24 young males treated and followed up for hyperactivity since childhood. Compared to 27 matched controls, adults with a history of hyperactivity had a significantly greater frequency of cerebral atrophy. No differences in cerebellar atrophy frequency or in lateral cerebral ventricle-to-brain ratio (VBR) were found. The possible associations of hyperactivity or perhaps stimulant drug treatment to atrophic brain changes are discussed.

AB - A computed tomographic (CT) brain scan study was conducted in 24 young males treated and followed up for hyperactivity since childhood. Compared to 27 matched controls, adults with a history of hyperactivity had a significantly greater frequency of cerebral atrophy. No differences in cerebellar atrophy frequency or in lateral cerebral ventricle-to-brain ratio (VBR) were found. The possible associations of hyperactivity or perhaps stimulant drug treatment to atrophic brain changes are discussed.

KW - Computerized tomography

KW - cerebellar atrophy

KW - cortical atrophy

KW - hyperactivity

KW - ventricular enlargment

UR - https://www.scopus.com/pages/publications/0022586243

UR - https://www.scopus.com/pages/publications/0022586243#tab=citedBy

U2 - 10.1016/0165-1781(86)90052-1

DO - 10.1016/0165-1781(86)90052-1

M3 - Article

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SN - 0165-1781

VL - 17

SP - 241

EP - 246

JO - Psychiatry Research

JF - Psychiatry Research

IS - 3

ER -

Cortical atrophy in young adults with a history of hyperactivity in childhood

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