Cortical atrophy in young adults with a history of hyperactivity in childhood

Henry A. Nasrallah, Jan Loney, Stephen C. Olson, Mona McCalley-Whitters, John Kramer, Charles G. Jacoby

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Abstract

A computed tomographic (CT) brain scan study was conducted in 24 young males treated and followed up for hyperactivity since childhood. Compared to 27 matched controls, adults with a history of hyperactivity had a significantly greater frequency of cerebral atrophy. No differences in cerebellar atrophy frequency or in lateral cerebral ventricle-to-brain ratio (VBR) were found. The possible associations of hyperactivity or perhaps stimulant drug treatment to atrophic brain changes are discussed.

Original languageEnglish (US)
Pages (from-to)241-246
Number of pages6
JournalPsychiatry Research
Volume17
Issue number3
DOIs
StatePublished - Mar 1986

Keywords

  • Computerized tomography
  • cerebellar atrophy
  • cortical atrophy
  • hyperactivity
  • ventricular enlargment

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    Nasrallah, H. A., Loney, J., Olson, S. C., McCalley-Whitters, M., Kramer, J., & Jacoby, C. G. (1986). Cortical atrophy in young adults with a history of hyperactivity in childhood. Psychiatry Research, 17(3), 241-246. https://doi.org/10.1016/0165-1781(86)90052-1