Correlates of excessive daytime sleepiness in Parkinson's disease

Jacob Wegelin, Patrick McNamara, Raymon Durso, Ariel Brown, Deirdre McLaren

Research output: Contribution to journalArticle

23 Scopus citations

Abstract

Measures of excessive daytime sleepiness, neuropsychologic function, and mood were assessed in twenty-two persons with mid-stage Parkinson's disease (PD) and sixteen age-matched healthy controls. Levodopa dose equivalents (LDE) were computed for the patients. While Epworth sleepiness score (ESS), Mini Mental State Exam, logical memory, Stroop, and the mood scales, reliably distinguished patients from controls, only the mood scales (especially anxiety) were reliably associated with ESS. LDE was not significantly associated with ESS. Excessive daytime sleepiness in patients with mid-stage PD may be more strongly related to anxiety than to other neuropsychologic dysfunction or dopaminergic dosing levels.

Original languageEnglish (US)
Pages (from-to)441-448
Number of pages8
JournalParkinsonism and Related Disorders
Volume11
Issue number7
DOIs
StatePublished - Nov 2005
Externally publishedYes

Keywords

  • Dopamine agonists
  • Excessive daytime sleepiness
  • Executive functions
  • Mood
  • Neuropsychology
  • Parkinson's disease

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