Correlates of comfort with alternative settings for HPV vaccine delivery

Annie Laurie McRee, Paul L. Reiter, Jessica K. Pepper, Noel T. Brewer

    Research output: Contribution to journalArticlepeer-review

    19 Scopus citations


    Low uptake of human papillomavirus (HPV) vaccine calls for innovative approaches. Offering the vaccine in settings outside the traditional medical home, such as schools and pharmacies, could increase use. We sought to characterize the acceptability of HPV vaccine delivery in these alternative settings using a national (US) sample of parents of adolescent males ages 11-17 y (n = 506) and their sons (n = 391) who completed our online surveys in Fall 2010. We used multivariable regression to identify correlates of parents' and sons' comfort with (i.e., acceptability of) alternative settings. Half of parents (50%) and over one-third of sons (37%) reported that they were comfortable with schools or pharmacies as locations for the sons to receive HPV vaccine. Parents and sons were more comfortable with HPV vaccination in alternative settings if the sons had not recently visited their health care providers or had previously received vaccines at school, or if parents and sons were comfortable talking with each other about new vaccines. Parents who perceived greater barriers to HPV vaccination were more comfortable with alternative settings, as were sons who perceived that their peers were more accepting of HPV vaccine (all p <0.05). Offering HPV vaccine in alternative settings may increase vaccination, especially among hard-to-reach adolescents. For example, our results suggest that offering the vaccine in alternative settings to boys who had not had recent health care visits could increase uptake by more than 10%. Study findings also highlight factors that should be addressed to maximize the potential success of HPV vaccination programs.

    Original languageEnglish (US)
    Pages (from-to)306-313
    Number of pages8
    JournalHuman Vaccines and Immunotherapeutics
    Issue number2
    StatePublished - 2013

    Bibliographical note

    Funding Information:
    Supported in part by a research grant from the Investigator-Initiated Studies Program of Merck Sharp and Dohme Corp. Additional support was provided by the American Cancer Society (MSRG-06-259-01-CPPB), the Cancer Control Education Program at UNC Lineberger Comprehensive Cancer Center (R25 CA57726), the National Institutes of Health (P50CA105632 and P30CA016058), and a NRSA in Primary Medical Care at the University of Minnesota (T32HP22239).

    Funding Information:
    A research grant from Merck Sharp and Dohme Corp. funded the study. Merck Sharp and Dohme Corp. played no role in the study design, planning, implementation, analysis or reporting of the findings. The opinions expressed in this paper are those of the authors and do not necessarily represent those of Merck Sharp and Dohme Corp. N.T.B. has also received grants and/or honoraria from Merck Sharp and Dohme and from GlaxoSmithKline.


    • Adolescents
    • HPV vaccine
    • Immunization
    • Patient acceptance of health care
    • Pharmacies
    • Schools

    PubMed: MeSH publication types

    • Journal Article
    • Research Support, N.I.H., Extramural
    • Research Support, Non-U.S. Gov't


    Dive into the research topics of 'Correlates of comfort with alternative settings for HPV vaccine delivery'. Together they form a unique fingerprint.

    Cite this