Skip to main navigation Skip to search Skip to main content

Correction to: Integrated Proteogenomic Characterization of Human High-Grade Serous Ovarian Cancer (Cell, (2016), 166, 3, (755-765), (S0092867416306730), 10.1016/j.cell.2016.05.069)

  • Hui Zhang
  • , Tao Liu
  • , Zhen Zhang
  • , Samuel H. Payne
  • , Bai Zhang
  • , Jason E. McDermott
  • , Jian Ying Zhou
  • , Vladislav A. Petyuk
  • , Li Chen
  • , Debjit Ray
  • , Shisheng Sun
  • , Feng Yang
  • , Lijun Chen
  • , Jing Wang
  • , Punit Shah
  • , Seong Won Cha
  • , Paul Aiyetan
  • , Sunghee Woo
  • , Yuan Tian
  • , Marina A. Gritsenko
  • Therese R. Clauss, Caitlin Choi, Matthew E. Monroe, Stefani Thomas, Song Nie, Chaochao Wu, Ronald J. Moore, Kun Hsing Yu, David L. Tabb, David Fenyö, Vineet Bafna, Yue Wang, Henry Rodriguez, Emily S. Boja, Tara Hiltke, Robert C. Rivers, Lori Sokoll, Heng Zhu, Ie Ming Shih, Leslie Cope, Akhilesh Pandey, Bing Zhang, Michael P. Snyder, Douglas A. Levine, Richard D. Smith, Daniel W. Chan, Karin D. Rodland

Research output: Contribution to journalComment/debatepeer-review

Abstract

(Cell 166, 755–765; July 28, 2016) Our paper characterized proteomics and phosphoproteomics data from high-grade serous ovarian cancer tumors. As part of this analysis, we, the authors, used machine learning to identify a set of protein signatures that were predictive of patient survival after treatment. We recently discovered that the code we used for this analysis selected incorrect signatures during the training phase, and these signatures were included as the protein weights listed in Table S6. The incorrect signatures in Table S6, if used on the complete proteomics dataset, would not produce the results shown in Figure 4. We have now corrected this issue in the updated table, and the combination of the resulting signatures produces the same results shown in Figure 4. Importantly, when we applied the corrected signatures to our prospective dataset (previously published in McDermott et al., 2020, 10.1016/j.xcrm.2020.100004), we obtained identical results, confirming the validity and predictive value of the corrected signatures. This error does not impact any of the reported results, figures, or conclusions in our manuscript. We have provided an updated Table S6 with the correct protein signatures linked below. We sincerely apologize for any confusion this error may have caused.

Original languageEnglish (US)
Pages (from-to)7016
Number of pages1
JournalCell
Volume188
Issue number24
DOIs
StatePublished - Nov 26 2025

Bibliographical note

Publisher Copyright:
© 2025 Elsevier Inc.

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

PubMed: MeSH publication types

  • Published Erratum

Fingerprint

Dive into the research topics of 'Correction to: Integrated Proteogenomic Characterization of Human High-Grade Serous Ovarian Cancer (Cell, (2016), 166, 3, (755-765), (S0092867416306730), 10.1016/j.cell.2016.05.069)'. Together they form a unique fingerprint.

Cite this