Correcting autoimmune anomalies in autoimmune disorders by immunological means, employing the modified vaccination technique

Arpad Zsigmond Barabas, Chad Douglas Cole, Arpad David Barabas, Richard Milton Graeff, Rene Lafreniere, Donald Mackay Weir

Research output: Contribution to journalReview articlepeer-review

11 Scopus citations

Abstract

Our research group has developed a new vaccination technique in experimental animals that has the potential of correcting autoimmune anomalies in humans such as autoimmune disorders, cancer, and chronic infections, both prophylactically and therapeutically. The vaccination method is called Modified Vaccination Technique (MVT). The MVT necessitates the introduction of a purified target antigen (ag) and a specific antibody (ab) against the target ag in the form of immune complex (IC) to evoke the desired immune response outcome by ab information transfer in the injected recipient. The injected IC produces the same class of ab in the host, with the same specificity against the target ag, as resides in the inoculum. The MVT promises to provide a means of upregulating beneficial immune events and downregulating undesirable immune responses in individuals, thereby re-establishing normalcy/tolerance to self.

Original languageEnglish (US)
Pages (from-to)552-557
Number of pages6
JournalAutoimmunity Reviews
Volume8
Issue number7
DOIs
StatePublished - Jun 1 2009

Keywords

  • Autoimmune anomalies
  • Modified vaccination technique
  • Prophylactic
  • Therapeutic
  • Tolerance to self

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