TY - JOUR
T1 - Correcting autoimmune anomalies in autoimmune disorders by immunological means, employing the modified vaccination technique
AU - Barabas, Arpad Zsigmond
AU - Cole, Chad Douglas
AU - Barabas, Arpad David
AU - Graeff, Richard Milton
AU - Lafreniere, Rene
AU - Weir, Donald Mackay
PY - 2009/6
Y1 - 2009/6
N2 - Our research group has developed a new vaccination technique in experimental animals that has the potential of correcting autoimmune anomalies in humans such as autoimmune disorders, cancer, and chronic infections, both prophylactically and therapeutically. The vaccination method is called Modified Vaccination Technique (MVT). The MVT necessitates the introduction of a purified target antigen (ag) and a specific antibody (ab) against the target ag in the form of immune complex (IC) to evoke the desired immune response outcome by ab information transfer in the injected recipient. The injected IC produces the same class of ab in the host, with the same specificity against the target ag, as resides in the inoculum. The MVT promises to provide a means of upregulating beneficial immune events and downregulating undesirable immune responses in individuals, thereby re-establishing normalcy/tolerance to self.
AB - Our research group has developed a new vaccination technique in experimental animals that has the potential of correcting autoimmune anomalies in humans such as autoimmune disorders, cancer, and chronic infections, both prophylactically and therapeutically. The vaccination method is called Modified Vaccination Technique (MVT). The MVT necessitates the introduction of a purified target antigen (ag) and a specific antibody (ab) against the target ag in the form of immune complex (IC) to evoke the desired immune response outcome by ab information transfer in the injected recipient. The injected IC produces the same class of ab in the host, with the same specificity against the target ag, as resides in the inoculum. The MVT promises to provide a means of upregulating beneficial immune events and downregulating undesirable immune responses in individuals, thereby re-establishing normalcy/tolerance to self.
KW - Autoimmune anomalies
KW - Modified vaccination technique
KW - Prophylactic
KW - Therapeutic
KW - Tolerance to self
UR - http://www.scopus.com/inward/record.url?scp=67349172922&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=67349172922&partnerID=8YFLogxK
U2 - 10.1016/j.autrev.2009.01.014
DO - 10.1016/j.autrev.2009.01.014
M3 - Review article
C2 - 19393215
AN - SCOPUS:67349172922
SN - 1568-9972
VL - 8
SP - 552
EP - 557
JO - Autoimmunity Reviews
JF - Autoimmunity Reviews
IS - 7
ER -