TY - JOUR
T1 - Coronary artery bypass graft surgery and cognitive performance
AU - Dupuis, Gilles
AU - Kennedy, Elaine
AU - Lindquist, Ruth
AU - Barton, Franca B.
AU - Terrin, Michael L.
AU - Hoogwerf, Byron J.
AU - Czajkowski, Susan M.
AU - Herd, J. Alan
PY - 2006/9
Y1 - 2006/9
N2 - BACKGROUND: Some studies have indicated a decline in patients' cognitive performance after coronary artery bypass graft surgery. OBJECTIVE: To evaluate cognitive performance before and after coronary artery bypass graft surgery. METHODS: Patients' cognitive performance before and after coronary artery bypass graft surgery was evaluated in a prospective observational multicenter study in 5 academic medical centers. A total of 242 men and 123 women were evaluated before surgery; 333 men and 216 women, 5 to 11 months after surgery (197 men and 99 women were evaluated both before and after surgery). Verbal ability, attention/concentration, logical/verbal and visual memory, and facial recognition were measured. Data on demographic, medical, and psychosocial characteristics also were collected. RESULTS: After surgery, patients' overall performance improved (P <. 001) for attention/concentration, verbal fluency, and logical/verbal memory. Patients with more education (high school or greater) performed better on each test (P < .001) than did patients with less education. No strong effects of sex or age on cognitive performance were observed before or after surgery, and no important differences in sex, age, or education were associated with changes in scores from before to after surgery. CONCLUSION: On average, cognitive performance improved rather than declined after coronary artery bypass graft surgery. The improvements were consistent across sex, age, and education.
AB - BACKGROUND: Some studies have indicated a decline in patients' cognitive performance after coronary artery bypass graft surgery. OBJECTIVE: To evaluate cognitive performance before and after coronary artery bypass graft surgery. METHODS: Patients' cognitive performance before and after coronary artery bypass graft surgery was evaluated in a prospective observational multicenter study in 5 academic medical centers. A total of 242 men and 123 women were evaluated before surgery; 333 men and 216 women, 5 to 11 months after surgery (197 men and 99 women were evaluated both before and after surgery). Verbal ability, attention/concentration, logical/verbal and visual memory, and facial recognition were measured. Data on demographic, medical, and psychosocial characteristics also were collected. RESULTS: After surgery, patients' overall performance improved (P <. 001) for attention/concentration, verbal fluency, and logical/verbal memory. Patients with more education (high school or greater) performed better on each test (P < .001) than did patients with less education. No strong effects of sex or age on cognitive performance were observed before or after surgery, and no important differences in sex, age, or education were associated with changes in scores from before to after surgery. CONCLUSION: On average, cognitive performance improved rather than declined after coronary artery bypass graft surgery. The improvements were consistent across sex, age, and education.
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M3 - Article
C2 - 16926368
AN - SCOPUS:33845252123
SN - 1062-3264
VL - 15
SP - 471
EP - 479
JO - American Journal of Critical Care
JF - American Journal of Critical Care
IS - 5
ER -