Coordination microparticle vaccines engineered from tumor cell templates

Xiaoli Wang, Jiayi Liang, Chuangnian Zhang, Guilei Ma, Chun Wang, Deling Kong

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

A method for encapsulation of individual tumor cells with an epigallocatechin-3-gallate (EGCG)-Al(iii) coordination layer, which can be used as potential tumor vaccines, was developed. The interaction between microparticle vaccines and dendritic cells was investigated in vitro. The microparticles (∼10 μm) were efficiently internalized by DCs with enhanced uptake efficiency via actin polymerization and clathrin-mediated endocytosis.

Original languageEnglish (US)
Pages (from-to)1568-1571
Number of pages4
JournalChemical Communications
Volume55
Issue number11
DOIs
StatePublished - Jan 1 2019

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Clathrin
Cancer Vaccines
Vaccines
Encapsulation
Actins
Tumors
Polymerization
Cells
epigallocatechin gallate
Dendritic Cells

PubMed: MeSH publication types

  • Journal Article

Cite this

Coordination microparticle vaccines engineered from tumor cell templates. / Wang, Xiaoli; Liang, Jiayi; Zhang, Chuangnian; Ma, Guilei; Wang, Chun; Kong, Deling.

In: Chemical Communications, Vol. 55, No. 11, 01.01.2019, p. 1568-1571.

Research output: Contribution to journalArticle

Wang, Xiaoli ; Liang, Jiayi ; Zhang, Chuangnian ; Ma, Guilei ; Wang, Chun ; Kong, Deling. / Coordination microparticle vaccines engineered from tumor cell templates. In: Chemical Communications. 2019 ; Vol. 55, No. 11. pp. 1568-1571.
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