Cooperativity between Orthosteric Inhibitors and Allosteric Inhibitor 8-Anilino-1-Naphthalene Sulfonic Acid (ANS) in Cyclin-Dependent Kinase 2

Keyphrases

• Cyclin-dependent Kinase 2 (CDK2) 100%
• Cooperativity 100%
• Allosteric Inhibitor 100%
• Naphthalene Sulfonates 100%
• Roscovitine 40%
• Orthosteric 40%
• Kinase Inhibitor 20%
• Titration 20%
• Allosteric Kinase Inhibitor 20%
• Nuclear Magnetic Resonance 20%
• Active Sites 20%
• Nonoperative 20%
• Heteronuclear 20%
• Slow Exchange 20%
• Kinase Inhibition 20%
• Fast Exchange 20%
• Structural Homology 20%
• Binding Assay 20%
• Quantum Correlations 20%
• Allosteric Pocket 20%
• Single Quantum System 20%
• Dinaciclib 20%
• Positive Cooperativity 20%
• Cooperative Relationship 20%
• Selective Kinase Inhibitor 20%
• ATP Mimics 20%

Biochemistry, Genetics and Molecular Biology

• Cooperation 100%
• Cyclin-Dependent Kinase 2 100%
• Sulfonic Acid 100%
• Phosphotransferase 80%
• Kinase 80%
• Adenosine Triphosphate 40%
• Active Site 20%
• Structural Homology 20%

Pharmacology, Toxicology and Pharmaceutical Science

• 8-Anilinonaphthalene-1-Sulfonic Acid 100%
• Cyclin Dependent Kinase 2 100%
• Phosphotransferase Inhibitor 60%
• Roscovitine 40%
• Adenosine Triphosphate 40%
• Malignant Neoplasm 20%
• Phosphotransferase 20%
• Cyclin Dependent Kinase 2 Inhibitor 20%
• Dinaciclib 20%
• Diseases 20%