Convenient and efficient preparations of azodye-labeled peptides

Alan R. Katritzky, Qi Yin Chen, Srinivasa R. Tala

Research output: Contribution to journalArticle

13 Scopus citations

Abstract

N-(4-Arylazobenzoyl)-1H-benzotriazoles 15a, 15b react with dipeptides 12a-d, (12d+12d′) and tripeptides 14a, 14b to give azodye labeled-dipeptides (16a-e), (16d+16d′), (16e+16e′) and -tripeptides 16f, 16g in high yields (73-93%) with retention of chirality.

Original languageEnglish (US)
Pages (from-to)611-617
Number of pages7
JournalChemical Biology and Drug Design
Volume73
Issue number6
DOIs
StatePublished - Jun 1 2009

Keywords

  • Azodye
  • Benzotriazole methodology
  • N-protected(α-aminoacyl) benzotriazole
  • Photoisomerization
  • Small peptides

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