Control of flagellar length in Chlamydomonas

Paul A. Lefebvre, Catherine M. Asleson, Lai Wa Tam

Research output: Contribution to journalArticlepeer-review

7 Scopus citations


The flagella of the unicellular green alga Chlamydomonas reinhardtii are controlled by a number of sophisticated homeostatic mechanisms which ensure that the flagella are maintained at a specific length, and that each cell has two flagella of equal length. Mutants with defects in flagellar length control have been obtained, defining at least nine genes that are involved in the control of flagellar length and the equality of flagellar length. The active machinery involved in flagellar length control requires that cells precisely measure the length of their flagella and drastically alter flagellar protein production and assembly when necessary to maintain desired lengths.

Original languageEnglish (US)
Pages (from-to)317-323
Number of pages7
JournalSeminars in Developmental Biology
Issue number5
StatePublished - 1995

Bibliographical note

Funding Information:
Research in the Lefebvre laboratory was supported by a grant from the US Public Health Service (NIGMS 34437). C.M.A. was supported by a Research Training Group Grant BIR 9113444 from the National Science Foundation. L-W.T. was supported by a fellowship from the University of Minnesota Plant Molecular Genetics Institute, and by a National Research Service Award from the NIAID (F32 AI08942).


  • Chlamydomonas
  • flagella
  • mutants


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