A major epidemic of foot-and-mouth disease affected Argentina during 2001. The epidemic was controlled by mass-vaccination of the national herd and movement restrictions. The median herd disease reproduction ratio (R H) decreased significantly from 2.4 (before the epidemic was officially recognized) to 1.2 during the mass-vaccination campaign and <1 following the mass-vaccination campaign. The largest distance between two outbreaks was similar during (1905 km) and after (1890 km) the mass-vaccination. However, after mass-vaccination was completed, the proportion of herd outbreaks clustered decreased from 70.4% to 66.8%, respectively. Although a combination of vaccination and livestock-movement restrictions was effective in controlling the epidemic, 112 herd outbreaks occurred up to 6 months after the end of the mass-vaccination campaign. Mass-vaccination and movement restrictions might be an effective strategy to control FMD; however, the time taken to end large, national epidemics might be >1 year.
Bibliographical noteFunding Information:
The authors acknowledge the assistance of Dr. Ricardo Maresca and Dr. Bernardo Cosentino (Epidemiology Department, SENASA), who provided much of the epidemic information. This study was partly funded by a Global Initiative Faculty Grant, Purdue University International Programs.
- Foot-and-mouth disease
- Reproduction ratio
- Spatial distribution