Continuous magnetophoretic enrichment of rare tumor cells

D. Nawarathna; P. Kumaresan; Y. Zhang; B. Ferguson; S. H. Oh; K. S. Lam; H. T. Soh

Continuous magnetophoretic enrichment of rare tumor cells

D. Nawarathna
, P. Kumaresan
, Y. Zhang
, B. Ferguson
, S. H. Oh
, K. S. Lam
, H. T. Soh

Electrical and Computer Engineering

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

We present the Continuous-flow Magnetic Activated Cell Sorter (CMACS) device which is capable of enriching rare magnetic particles with high purity. The microfabricated ferromagnetic strips within the microfluidic channels create high magnetic field gradients, which generate the magnetophoretic separation forces. We report on the effective separation of magnetically labeled Human Lymphoma (Jurkat) cells from non-target cells and compare its performance against commercially available macro-scale systems.

Original language	English (US)
Title of host publication	Proceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007
Editors	Jean-Louis Viovy, Patrick Tabeling, Stephanie Descroix, Laurent Malaquin
Publisher	Chemical and Biological Microsystems Society
Pages	122-124
Number of pages	3
ISBN (Electronic)	9780979806407
State	Published - 2007
Event	11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007 - Paris, France Duration: Oct 7 2007 → Oct 11 2007

Publication series

Name	Proceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007

Conference

Conference	11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007
Country/Territory	France
City	Paris
Period	10/7/07 → 10/11/07

Bibliographical note

Publisher Copyright:
© 2007 CBMS.

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Magnetic separation
Rare cell sorting

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Nawarathna, D., Kumaresan, P., Zhang, Y., Ferguson, B., Oh, S. H., Lam, K. S., & Soh, H. T. (2007). Continuous magnetophoretic enrichment of rare tumor cells. In J.-L. Viovy, P. Tabeling, S. Descroix, & L. Malaquin (Eds.), Proceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007 (pp. 122-124). (Proceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007). Chemical and Biological Microsystems Society.

Continuous magnetophoretic enrichment of rare tumor cells. / Nawarathna, D.; Kumaresan, P.; Zhang, Y. et al.
Proceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007. ed. / Jean-Louis Viovy; Patrick Tabeling; Stephanie Descroix; Laurent Malaquin. Chemical and Biological Microsystems Society, 2007. p. 122-124 (Proceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Nawarathna, D, Kumaresan, P, Zhang, Y, Ferguson, B, Oh, SH, Lam, KS & Soh, HT 2007, Continuous magnetophoretic enrichment of rare tumor cells. in J-L Viovy, P Tabeling, S Descroix & L Malaquin (eds), Proceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007. Proceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007, Chemical and Biological Microsystems Society, pp. 122-124, 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007, Paris, France, 10/7/07.

Nawarathna D, Kumaresan P, Zhang Y, Ferguson B, Oh SH, Lam KS et al. Continuous magnetophoretic enrichment of rare tumor cells. In Viovy JL, Tabeling P, Descroix S, Malaquin L, editors, Proceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007. Chemical and Biological Microsystems Society. 2007. p. 122-124. (Proceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007).

Nawarathna, D. ; Kumaresan, P. ; Zhang, Y. et al. / Continuous magnetophoretic enrichment of rare tumor cells. Proceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007. editor / Jean-Louis Viovy ; Patrick Tabeling ; Stephanie Descroix ; Laurent Malaquin. Chemical and Biological Microsystems Society, 2007. pp. 122-124 (Proceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007).

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abstract = "We present the Continuous-flow Magnetic Activated Cell Sorter (CMACS) device which is capable of enriching rare magnetic particles with high purity. The microfabricated ferromagnetic strips within the microfluidic channels create high magnetic field gradients, which generate the magnetophoretic separation forces. We report on the effective separation of magnetically labeled Human Lymphoma (Jurkat) cells from non-target cells and compare its performance against commercially available macro-scale systems.",

keywords = "Magnetic separation, Rare cell sorting",

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AU - Lam, K. S.

AU - Soh, H. T.

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KW - Rare cell sorting

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BT - Proceedings of the 11th International Conference on Miniaturized Systems for Chemistry and Life Sciences, uTAS 2007

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A2 - Descroix, Stephanie

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ER -

Continuous magnetophoretic enrichment of rare tumor cells

Abstract

Publication series

Conference

Bibliographical note

UN SDGs

Keywords

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