Continuous glucose monitoring following pancreatectomy with islet autotransplantation in children

Deborah A. Elder, Jose M. Jiminez-Vega, Lindsey N. Hornung, Ranjit S. Chima, Maisam Abu-El-Haija, Tom K. Lin, Joseph J. Palermo, Jaimie D. Nathan

Research output: Contribution to journalArticlepeer-review

13 Scopus citations

Abstract

Aim was to determine whether CGM could accurately monitor blood glucose concentration in the immediate postoperative period following pancreatectomy with IAT in children. CGM was used in nine patients undergoing IAT at our institution between April 2015 and September 2016 (eight total pancreatectomy and one subtotal pancreatectomy). MAD and MARD of CGM values compared to time-matched serum blood glucose were calculated during the first 5 days of ICU admission. Goal range was defined as 70-140 mg/dL and out-of-range was >140 mg/dL or <70 mg/dL. Of 89 time-matched measures found, 75% of CGM values were within 15 mg/dL, and 51% were within 10 mg/dL, compared to serum glucose. MAD was 11.6 mg/dL, and MARD was 10.6%. CGM values did not differ from serum glucose (P=.74). By Clarke error grid analysis, 100% of paired values were in clinically acceptable zones. By surveillance error grid analysis, 96% of paired values were within clinically acceptable agreement. CGM is a reliable tool in monitoring glycemic control in the immediate postoperative period following pancreatectomy with IAT in children.

Original languageEnglish (US)
Article numbere12998
JournalPediatric transplantation
Volume21
Issue number7
DOIs
StatePublished - Nov 2017

Bibliographical note

Publisher Copyright:
© 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd

Keywords

  • euglycemia
  • mean absolute difference
  • mean absolute relative difference
  • pancreatitis

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