Consumption of prunes as a source of dietary fiber in men with mild hypercholesterolemia

Lesley F. Tinker, Barbara O. Schneeman, Paul A. Davis, Daniel D. Gallaher, Carolyn R. Waggoner

Research output: Contribution to journalArticlepeer-review

84 Scopus citations

Abstract

Forty-one free-living adult men with mild hypercholesterolemia (5.2-7.5 mmol/L) voluntarily participated in an 8-wk crossover study designed to determine the effect of prunes as a source of fiber on plasma cholesterol and on fecal output and bile acid concentration. During the prune period, subjects supplemented their usual diets with 12 prunes (100 g; 6g dietary fiber) daily. Plasma low-density-lipoprotein cholesterol was significantly lower after the prune period (3.9 mmol/L) than after the grape-juice-control period (4.1 mmol/L). Fecal bile acid concentration of lithocholic acid was significantly lower after the prune period (0.95 mg bile acid/g dry wt stool) than after the grape-juice-control period (1.20 mg bile acid/g dry wt stool). Both fecal wet and dry weights were ∼20% higher after the prune period than after the grape-juice-control period. Total bile acids (mg/72 h) did not significantly differ between experimental periods.

Original languageEnglish (US)
Pages (from-to)1259-1265
Number of pages7
JournalAmerican Journal of Clinical Nutrition
Volume53
Issue number5
DOIs
StatePublished - May 1991
Externally publishedYes

Keywords

  • Bile acids
  • Cholesterol
  • Dietary fiber
  • Human
  • Hypercholesterolemia
  • Pectin
  • Prune

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