Abstract
Fourteen compounds were isolated from the roots of Cynanchum auriculatum and their chemical structures were identified as β-sitosterol (1), acetovanillone (2), p-hydroxyacetophenone (3), 2,4-dihydroxyacetophenone (4), 2,5-dihydroxyacetophenone (5), cynandione A (6), methyleugenol (7), daucosterol (8), Succinic acid (9), cynauriculoside A (10), wilfoside C3N (11), wilfoside C1N (12), wilfoside K1N (13) and wilfoside C1G (14). Among them, compounds 2-5 were isolated from this plant for the first time. And 2, 5-dihydroxyacetophenone (5) showed the most potent inhibitory effect on melanogenesis in B-16 mouse melanoma cell lines with IC50 value of 20 μM.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 238-244 |
| Number of pages | 7 |
| Journal | Korean Journal of Pharmacognosy |
| Volume | 41 |
| Issue number | 4 |
| State | Published - Dec 1 2010 |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
-
SDG 3 Good Health and Well-being
Keywords
- 2, 5-dihydroxyacetophenone
- B16 cell lines
- Cynanchum auriculatum
- Melanogenesis
Fingerprint
Dive into the research topics of 'Constituents of Cynanchum auriculatum and their inhibitory effect on melanogenesis in B16 mouse melanoma cell lines'. Together they form a unique fingerprint.Cite this
- APA
- Standard
- Harvard
- Vancouver
- Author
- BIBTEX
- RIS