Consistency of the tobacco withdrawal syndrome

John R. Hughes, Dorothy K Hatsukami, Roy W. Pickens, Dace S. Svikis

Research output: Contribution to journalArticlepeer-review

27 Scopus citations


The consistency of the tobacco withdrawal syndrome across repeated periods of abstinence was tested using a modified A-B-A-B design. The large majority of the signs and symptoms of tobacco withdrawal occured during abstinence, returned to baseline, and then recurred during a second abstinence period. This finding suggests that the syndrome is reliable and can be studied with within-subject designs.

Original languageEnglish (US)
Pages (from-to)409-412
Number of pages4
JournalAddictive Behaviors
Issue number4
StatePublished - 1984

Bibliographical note

Funding Information:
The research ias funded by a NIDA research grant (2 ROl DA02988-03), an NHLBI training grant (5T32 HL07328-04), and funds from the State of Minnesota for psychiatric research. The authors thank Kathy Carroll and Alice Luknic for their help.


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