Consensus recommendations for use of long-acting antiretroviral medications in the treatment and prevention of HIV-1: Endorsed by the American Academy of HIV Medicine, American College of Clinical Pharmacy, Canadian HIV and Viral Hepatitis Pharmacists Network, European AIDS Clinical Society, and Society of Infectious Diseases Pharmacists

Elizabeth M. Sherman, Allison L. Agwu, Juan Ambrosioni, Georg M.N. Behrens, Carolyn Chu, Lauren F. Collins, Humberto R. Jimenez, David E. Koren, Leslie McGorman, Nancy N. Nguyen, Melanie R. Nicol, Neha Sheth Pandit, Natacha Pierre, Kimberly K. Scarsi, Gary F. Spinner, Alice Tseng, Jeremy D. Young, Melissa E. Badowski

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Five long-acting (LA) antiretrovirals (ARVs) are currently available in a limited number of countries worldwide for HIV-1 prevention or treatment—cabotegravir, rilpivirine, lenacapavir, ibalizumab, and dapivirine. Implementing use of LA ARVs into routine clinical practice requires significant changes to the current framework of HIV-1 prevention, treatment, and service provision. Given the novelty, complexity, and interdisciplinary requirements needed to safely and optimally utilize LA ARVs, consensus recommendations on the use of LA ARVs will assist clinicians in optimizing use of these agents. The purpose of these recommendations is to provide guidance for the clinical use of LA ARVs for HIV-1 treatment and prevention. In addition, future areas of research are also identified and discussed.

Original languageEnglish (US)
Pages (from-to)494-538
Number of pages45
JournalPharmacotherapy
Volume44
Issue number7
DOIs
StatePublished - Jul 2024

Bibliographical note

Publisher Copyright:
© 2024 The Authors. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy published by Wiley Periodicals LLC on behalf of Pharmacotherapy Publications, Inc.

Keywords

  • antiretrovirals
  • HIV
  • long acting
  • pre-exposure prophylaxis
  • prevention
  • treatment

PubMed: MeSH publication types

  • Journal Article
  • Practice Guideline

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