Abstract
TARGET POPULATIONS: Adults with solid brain metastases who have not experienced a seizure. QUESTION 1: Do prophylactic antiepileptic drugs (AEDs) decrease the risk of seizures in nonsurgical patients with brain metastases who are otherwise seizure-free? RECOMMENDATION: Level 3: Prophylactic AEDs are not recommended for patients with brain metastases who did not undergo surgical resection and are otherwise seizure-free. QUESTION 2: Do prophylactic AEDs decrease the risk of seizures in patients with brain metastases and no prior history of seizures in the postoperative setting? RECOMMENDATION: Level 3: Routine postcraniotomy AED use for seizure-free patients with brain metastases is not recommended. The full guideline can be found at: https://www.cns.org/guidelines/guidelines-treatmentadults-metastatic-brain-tumors/chapter-8.
Original language | English (US) |
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Pages (from-to) | E195-E197 |
Journal | Clinical Neurosurgery |
Volume | 84 |
Issue number | 3 |
DOIs | |
State | Published - Mar 1 2019 |
Keywords
- Antiepileptic drugs
- Cerebral metastases
- Craniotomy
- Seizure
PubMed: MeSH publication types
- Journal Article