We describe herein the congenital malformations of the middle and inner ears in temporal bones of parabiotic, monozygotic twins. Temporal bones were removed from twin B, who had no fetal cardiac activity and was born dead at 23-4/7 weeks, and twin A, the donor or 'pump' twin in intrauterine life, who died shortly after birth at 20-6/7 weeks. The temporal bones were processed routinely in celoidin, stained with hematoxylin and eosin, and examined by light microscopy. We found that twin B had Mondini's dysplasia with associated deformities of the middle ear and in general showed more developmental anomalies than twin A, and we conclude that Mondini's dysplasia with anomalies of the middle ear may occur in the parabiotic twin syndrome, and the abnormalities may be explainable as the result of vascular disturbance, which also causes other lesions in these unusual cases.
|Original language||English (US)|
|Number of pages||4|
|Journal||American Journal of Otolaryngology - Head and Neck Medicine and Surgery|
|State||Published - Jan 1 2000|
Bibliographical noteFunding Information:
From the *Department of Otolaryngology, Celal Bayar Untversity Medical School, Mantsa, Turkey, tOtitis Medta Research Center, Department of Otolaryngology, University of Minnesota, Minneapohs, MN; *International Hear-mg Foundatton, Mmneapohs; and the §Minnesota Ear Head and Neck Clinic, Mmneapohs, MN Supported m part by NIH-NIDCD Grant No P50DC03093001, by the Lions Internattonal of Mmne-sota and the International Hearing Foundation, Minneapolis, MN. Address repnnt requests to Patncla A Schachern, BS, Rm 226 Lions Research Labs, 2001 6th St SE, Mmneapo-Its, MN 55455 Copyrtght© 2000 by W B Saunders Company 0196-0709/00/2101-0008510.00/0