Confocal microscopy in posterior polymorphous corneal dystrophy

Auguste G.Y. Chiou; Stephen C. Kaufman; Roger W. Beuerman; Dmitri Maitchouk; Herbert E. Kaufman

doi:10.1159/000027423

Confocal microscopy in posterior polymorphous corneal dystrophy

Auguste G.Y. Chiou, Stephen C. Kaufman, Roger W. Beuerman, Dmitri Maitchouk, Herbert E. Kaufman

Research output: Contribution to journal › Article › peer-review

25 Scopus citations

Abstract

Purpose: To report the distinguishing characteristics of posterior polymorphous corneal dystrophy (PPMD) using confocal microscopy. Material and Methods: Two consecutive patients with PPMD were prospectively examined using a white-light tandem scanning confocal microscope with a 24 x /0.60 contact objective. Results: At the level of Descement's membrane, roundish hyporeflective images were found in 1 patient. In the other patient, hyporeflective bands were detected. In both patients, patchy hyperreflective areas were identified. Conclusion: Confocal microscopy may allow diagnosis of PPMD by demonstrating the alterations in Descement's membrane. This technique is especially valuable in cases of endothelial decompensation, where slit- lamp and specular microscopy may fail to demonstrate changes in Descement's membrane.

Original language	English (US)
Pages (from-to)	211-213
Number of pages	3
Journal	Ophthalmologica
Volume	213
Issue number	4
DOIs	https://doi.org/10.1159/000027423
State	Published - Jul 1999
Externally published	Yes

Keywords

Confocal microscopy
Posterior polymorphus corneal dystrophy

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10.1159/000027423

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title = "Confocal microscopy in posterior polymorphous corneal dystrophy",

abstract = "Purpose: To report the distinguishing characteristics of posterior polymorphous corneal dystrophy (PPMD) using confocal microscopy. Material and Methods: Two consecutive patients with PPMD were prospectively examined using a white-light tandem scanning confocal microscope with a 24 x /0.60 contact objective. Results: At the level of Descement's membrane, roundish hyporeflective images were found in 1 patient. In the other patient, hyporeflective bands were detected. In both patients, patchy hyperreflective areas were identified. Conclusion: Confocal microscopy may allow diagnosis of PPMD by demonstrating the alterations in Descement's membrane. This technique is especially valuable in cases of endothelial decompensation, where slit- lamp and specular microscopy may fail to demonstrate changes in Descement's membrane.",

keywords = "Confocal microscopy, Posterior polymorphus corneal dystrophy",

author = "Chiou, {Auguste G.Y.} and Kaufman, {Stephen C.} and Beuerman, {Roger W.} and Dmitri Maitchouk and Kaufman, {Herbert E.}",

year = "1999",

month = jul,

doi = "10.1159/000027423",

language = "English (US)",

volume = "213",

pages = "211--213",

journal = "Ophthalmologica",

issn = "0030-3755",

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TY - JOUR

T1 - Confocal microscopy in posterior polymorphous corneal dystrophy

AU - Chiou, Auguste G.Y.

AU - Kaufman, Stephen C.

AU - Beuerman, Roger W.

AU - Maitchouk, Dmitri

AU - Kaufman, Herbert E.

PY - 1999/7

Y1 - 1999/7

N2 - Purpose: To report the distinguishing characteristics of posterior polymorphous corneal dystrophy (PPMD) using confocal microscopy. Material and Methods: Two consecutive patients with PPMD were prospectively examined using a white-light tandem scanning confocal microscope with a 24 x /0.60 contact objective. Results: At the level of Descement's membrane, roundish hyporeflective images were found in 1 patient. In the other patient, hyporeflective bands were detected. In both patients, patchy hyperreflective areas were identified. Conclusion: Confocal microscopy may allow diagnosis of PPMD by demonstrating the alterations in Descement's membrane. This technique is especially valuable in cases of endothelial decompensation, where slit- lamp and specular microscopy may fail to demonstrate changes in Descement's membrane.

AB - Purpose: To report the distinguishing characteristics of posterior polymorphous corneal dystrophy (PPMD) using confocal microscopy. Material and Methods: Two consecutive patients with PPMD were prospectively examined using a white-light tandem scanning confocal microscope with a 24 x /0.60 contact objective. Results: At the level of Descement's membrane, roundish hyporeflective images were found in 1 patient. In the other patient, hyporeflective bands were detected. In both patients, patchy hyperreflective areas were identified. Conclusion: Confocal microscopy may allow diagnosis of PPMD by demonstrating the alterations in Descement's membrane. This technique is especially valuable in cases of endothelial decompensation, where slit- lamp and specular microscopy may fail to demonstrate changes in Descement's membrane.

KW - Confocal microscopy

KW - Posterior polymorphus corneal dystrophy

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Confocal microscopy in posterior polymorphous corneal dystrophy

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