Confocal microscopy in posterior polymorphous corneal dystrophy

Auguste G.Y. Chiou, Stephen C. Kaufman, Roger W. Beuerman, Dmitri Maitchouk, Herbert E. Kaufman

Research output: Contribution to journalArticlepeer-review

26 Scopus citations


Purpose: To report the distinguishing characteristics of posterior polymorphous corneal dystrophy (PPMD) using confocal microscopy. Material and Methods: Two consecutive patients with PPMD were prospectively examined using a white-light tandem scanning confocal microscope with a 24 x /0.60 contact objective. Results: At the level of Descement's membrane, roundish hyporeflective images were found in 1 patient. In the other patient, hyporeflective bands were detected. In both patients, patchy hyperreflective areas were identified. Conclusion: Confocal microscopy may allow diagnosis of PPMD by demonstrating the alterations in Descement's membrane. This technique is especially valuable in cases of endothelial decompensation, where slit- lamp and specular microscopy may fail to demonstrate changes in Descement's membrane.

Original languageEnglish (US)
Pages (from-to)211-213
Number of pages3
Issue number4
StatePublished - Jul 1999
Externally publishedYes


  • Confocal microscopy
  • Posterior polymorphus corneal dystrophy


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