Abstract
Background: The purpose of the study was to assess the appearance of lattice corneal dystrophy by means of white-light confocal microscopy. Methods: Two consecutive patients with lattice corneal dystrophy were prospectively examined. In vivo white-light tandem-scanning confocal microscopy was performed in the right eye of the first patient. Her left eye had undergone penetrating keratoplasty 4 years earlier. Histologic findings of the corneal button were compared with confocal microscopic findings of the right eye. The other patient was monocular and confocal microscopy was performed only in the non-seeing eye. Results: In both patients, linear and branching structures with changing reflectivity and poorly demarcated margins were visualized in the stroma. The linear structures measured approximately 40-80 μm in width. Conclusion: Lattice corneal dystrophy presents characteristic linear images on confocal microscopy and should not be misdiagnosed as fungal hyphae in cases of corneal infection.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 697-701 |
| Number of pages | 5 |
| Journal | Graefe's Archive for Clinical and Experimental Ophthalmology |
| Volume | 237 |
| Issue number | 8 |
| DOIs | |
| State | Published - Aug 1999 |
| Externally published | Yes |
Bibliographical note
Funding Information:Acknowledgements This study was supported in part by US Public Health Service grants EY00346 (S.C.K.), EY02580 (H.E.K.), and EY02377 (H.E.K.) from the National Eye Institute, National Institutes of Health, Bethesda, Md.; Department of the Army, Cooperative Agreement DAMD17–93-V-3013 (this does not necessarily reflect the position or the policy of the government, and no official endorsement should be inferred) (R.W.B., H.E.K.); an unrestricted departmental grant from Research to Prevent Blindness, Inc., New York City; Société Académique Vaudoise (A.G.-Y.C.), Switzerland; the Swiss National Research Foundation (A.G.-Y.C.), Switzerland; and the Verrey Foundation (A.G.-Y.C.), Switzerland.