Confirmation of Ureteric Patency During Cystoscopy Using Phenazopyridine HCl: A Low-cost Approach

Jane Y.C. Hui, Marie Andrée Harvey, Shawna L. Johnston

Research output: Contribution to journalArticlepeer-review

19 Scopus citations

Abstract

Objective: To describe the use of oral phenazopyridine (Pyridium) prior to pelvic surgery to facilitate intraoperative confirmation of ureteric patency. Materials and Methods: We performed a chart review of women given phenazopyridine preoperatively prior to pelvic surgery in a tertiary care centre between July 2004 and June 2005. The primary outcome was the cystoscopic observation of bilateral ureteric urine efflux. Secondary outcomes included the visualization of bladder mucosa during cystoscopy, postoperative complications, and urinary tract injury diagnosed postoperatively (i.e., missed intraoperatively). Results: Pelvic reconstructive surgery requiring intraoperative cystoscopy was performed in 124 women. Bilateral ureteric patency and bladder mucosal integrity was confirmed in all cases. Phenazopyridine was well tolerated by all patients, and its use was unequivocally documented in 32 subjects whose chart was reviewed to determine postoperative course. Bladder mucosal appearance was unaltered. Dye continued to be excreted during prolonged procedures. Postoperatively, no ureteric injuries were subsequently diagnosed in any patients. The cost per patient of phenazopyridine ($0.29) is substantially lower than indigo carmine ($34.50). Conclusion: Preoperative oral phenazopyridine is an inexpensive and safe dye that assists effectively in the confirmation of ureteric patency when cystoscopy is planned during pelvic surgery.

Original languageEnglish (US)
Pages (from-to)845-849
Number of pages5
JournalJournal of Obstetrics and Gynaecology Canada
Volume31
Issue number9
DOIs
StatePublished - 2009

Bibliographical note

Funding Information:
Financial Support for this study was provided by Queen’s University Summer Research Student Program.

Publisher Copyright:
© 2009 Society of Obstetricians and Gynaecologists of Canada.

Keywords

  • Cystoscopy
  • Pelvic floor surgery
  • Phenazopyridine
  • Stress/complications
  • Stress/surgery
  • Ureter injuries
  • Urinary incontinence
  • Urinary incontinence

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