Abstract
Avian infection studies with influenza A are an important means of assessing host susceptibility, viral pathogenesis, host responses to infection, mechanisms of transmission, viral pathotype, and viral evolution. Complex systems and natural settings may also be explored with carefully designed infection studies. In this chapter, we explore the elements of infection studies, general guidelines for choosing a virus to use, host selection, and many aspects of study design.
Original language | English (US) |
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Pages (from-to) | 195-209 |
Number of pages | 15 |
Journal | Methods in molecular biology (Clifton, N.J.) |
Volume | 2123 |
DOIs | |
State | Published - Jan 1 2020 |
Bibliographical note
Publisher Copyright:© This is a U.S. government work and not under copyright protection in the U.S.; foreign copyright protection may apply 2020.
Keywords
- Avian
- Challenge
- Host
- Infection
- Influenza
- Inoculation
- Pathogenesis
- Sample
- Shedding
- Transmission
PubMed: MeSH publication types
- Journal Article
- Review