Computed tomographic appearance of lissencephaly syndromes

W. B. Dobyns, C. W. McCluggage

Research output: Contribution to journalArticlepeer-review

26 Scopus citations


Lissencephaly is a rare malformation of the human brain manifest by a smooth cerebral surface. It is usually associated with other brain anomalies. The computed tomographic appearance in nine patients with lissencephaly, representing several separate types and syndromes, is reported. Common manifestations include a smooth cerebral surface and absent opercula that may lend a figure-eight appearance to the brain and smooth subsurface lines that represent abnormal cortical layers or an abnormal white-gray interface.

Original languageEnglish (US)
Pages (from-to)545-550
Number of pages6
JournalAmerican Journal of Neuroradiology
Issue number4
StatePublished - 1985
Externally publishedYes


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