Composite block polymer-microfabricated silicon nanoporous membrane

Eric E. Nuxoll, Marc A. Hillmyer, Ruifang Wang, C. Leighton, Ronald A. Siegel

Research output: Contribution to journalArticlepeer-review

54 Scopus citations


Block polymers offer an attractive route to densely packed, monodisperse nanoscale pores. However, their fragility as thin films complicates their use as membranes. By integrating a block polymer film with a thin (100 μ) silicon substrate, we have developed a composite membrane providing both nanoscale size exclusion and fast transport of small molecules. Here we describe the fabrication of this membrane, evaluate its mechanical integrity, and demonstrate its transport properties for model solutes of large and small molecular weight. The ability to block large molecules without hindering smaller ones, coupled with the potential for surface modification of the polymer and the microelectromechanical system style of support, makes this composite membrane an attractive candidate for interfacing implantable sensing and drug-delivery devices with biological hosts.

Original languageEnglish (US)
Pages (from-to)888-893
Number of pages6
JournalACS Applied Materials and Interfaces
Issue number4
StatePublished - Apr 29 2009


  • block polymer
  • membrane
  • microelectromechanical system
  • nanoporous
  • size selectivity


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