Complications of chronic pancreatitis in children

Emily Perito, Tanja Gonska, Melena D. Bellin, Sarah Jane Schwarzenberg

Research output: Contribution to journalReview articlepeer-review

3 Scopus citations


Purpose of reviewIn children, chronic pancreatitis is infrequent but may be associated with serious complications, including severe pain that limits activities, exocrine and endocrine pancreatic insufficiency and malnutrition. Investigation into pediatric chronic pancreatitis has transitioned from single center reports to multicenter, protocol-driven studies. As a result, we now have information on much larger numbers of children with chronic pancreatitis, allowing a more reliable understanding of the complications of chronic pancreatitis.Recent findingsA high percentage of children with chronic pancreatitis use opioids frequently to control pain. About a quarter of children with chronic pancreatitis have exocrine pancreatic insufficiency, and about 6% have pancreatogenic diabetes. Mild malnutrition and low bone density are both common in children with chronic pancreatitis.SummaryLarge multicenter and single-center observational studies have allowed us to more accurately assess complications of chronic pancreatitis in children. These studies demonstrate the need for examination of therapies for these complications in children.

Original languageEnglish (US)
Pages (from-to)498-503
Number of pages6
JournalCurrent opinion in gastroenterology
Issue number5
StatePublished - Sep 1 2021

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Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.


  • exocrine pancreatic insufficiency
  • opioid
  • pancreatogenic diabetes


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