Complete heart block in association with graft-versus-host disease

A. L. Gilman, N. W. Kooy, D. L. Atkins, Z. Ballas, S. Rumelhart, M. Holida, N. Lee, F. Goldman

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19 Scopus citations

Abstract

An infant who received haploidentical BM for severe combined immunodeficiency (SCID) developed acute, reversible complete heart block in association with an exacerbation of GVHD. Respiratory distress and myocardial dysfunction were also seen with this and previous GVHD exacerbations. The patient had not received chemotherapy or radiation prior to BMT. The complete heart block resolved after 1 week of intensive immunosuppression. The association of complete heart block with GVHD is important because the heart block is potentially reversible with prompt, aggressive control of the GVHD.

Original languageEnglish (US)
Pages (from-to)85-88
Number of pages4
JournalBone marrow transplantation
Volume21
Issue number1
DOIs
StatePublished - Jan 1 1998

Keywords

  • Arrhythmia
  • Bone marrow transplantation
  • Cardiac
  • Graft-versus-host disease
  • Heart block

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  • Cite this

    Gilman, A. L., Kooy, N. W., Atkins, D. L., Ballas, Z., Rumelhart, S., Holida, M., Lee, N., & Goldman, F. (1998). Complete heart block in association with graft-versus-host disease. Bone marrow transplantation, 21(1), 85-88. https://doi.org/10.1038/sj.bmt.1701038