Complete genome sequence of pathogenic guinea pig cytomegalovirus from salivary gland homogenates of infected animals

Dongmei Yang, Kristen Tamburro, Dirk Dittmer, Xiaohong Cui, Michael A. McVoy, Nelmary Hernandez-Alvarado, Mark R. Schleiss

Research output: Contribution to journalArticlepeer-review

14 Scopus citations

Abstract

The sequence of guinea pig cytomegalovirus (GPCMV) was determined by direct sequencing of salivary gland homogenates obtained following sustained, serial in vivo passage of pathogenic virus in guinea pigs. The 233,501-nucleotide salivary gland (SG) genome was noted to have 11 differences compared to the tissue culture-passaged virus, although no variations were noted in putative protein coding sequences.

Original languageEnglish (US)
Article numbere00054-13
JournalGenome Announcements
Volume1
Issue number2
DOIs
StatePublished - 2013

Bibliographical note

Funding Information:
This work was supported by NIH grants CA019014, HD044864, and HD038416. Helpful discussions with Martin G. Myers, Galveston, TX, are gratefully acknowledged (M.R.S.).

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