Comparison of versions 1.0 and 1.5 of the UltraSensitive AMPLICOR HIV-1 MONITOR test for subjects with low viral load

J. Brooks Jackson, Estelle Piwowar-Manning, Le Tanya Johnson-Lewis, Roland Bassett, Lisa M. Demeter, Donald Brambilla

Research output: Contribution to journalArticlepeer-review

7 Scopus citations

Abstract

We compared the performance of two UltraSensitive AMPLICOR HIV-1 MONITOR kits (version 1.5 [v1.5] versus v1.0) by retesting 404 plasma samples with low viral loads (<3,000 copies/mi) with both kits. With 292 samples that initially had <50 copies/mi by the v1.0 kit, the v1.5 assay was more sensitive than the v1.0 assay for samples with human immunodeficiency virus type 1 RNA near the 50-copy/ml cutoff (P = 0.0146). Median numbers of copies per milliliter were similar for 112 samples with 50 to 3,000 copies/mi with no difference in sensitivity with a 200-copy/ml cutoff.

Original languageEnglish (US)
Pages (from-to)2774-2776
Number of pages3
JournalJournal of clinical microbiology
Volume42
Issue number6
DOIs
StatePublished - Jun 2004

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