Comparison of the Hoesch and the Watson-Schwartz tests for urinary porphobilinogen

C. A. Pierach, R. Cardinal, I. Bossenmaier, C. J. Watson

Research output: Contribution to journalArticlepeer-review

23 Scopus citations

Abstract

A comparison of the Hoesch and the Watson-Schwartz tests shows that the latter, although slightly more complicated, generally yields more concise results and is superior in sensitivity and specificity for porphobilinogen. The recommendation of the Hoesch test for use as a 'bedside screening' method seems unrealistic. Before the diagnosis of an 'inducible' porphyria is made, a positive Hoesch test requires that indoles, indoleacetic acid, methyldopa, end-stage alcoholic malnutrition, and phenazopyridine HCl be excluded, to avoid misinterpretation.

Original languageEnglish (US)
Pages (from-to)1666-1668
Number of pages3
JournalClinical chemistry
Volume23
Issue number9
DOIs
StatePublished - Jan 1 1977

Fingerprint Dive into the research topics of 'Comparison of the Hoesch and the Watson-Schwartz tests for urinary porphobilinogen'. Together they form a unique fingerprint.

Cite this