Abstract
Although both NEM and IA completely inhibited G3PD activity and decreased RBC ATP levels 40%, IA produced little effect on RBC filterability whereas NEM greatly reduced the filtration rate. IA caused only an isolated increase of band 6 (G3PD) and no change in membrane protein content. However, the decreased filter-ability of NEM-treated RBC was associated with significantly increased membrane-associated nonhemoglobin protein which appeared as a complex array of polypeptide bands on PAGE SDS.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 318-321 |
| Number of pages | 4 |
| Journal | Proceedings of the Society for Experimental Biology and Medicine |
| Volume | 152 |
| Issue number | 3 |
| DOIs | |
| State | Published - Jul 1976 |