Comparison of impedance cardiography with indirect fick (CO2) method of measuring cardiac output in healthy children during exercise

Paul Pianosi; Daniel Garros

doi:10.1016/S0002-9149(97)89210-7

Comparison of impedance cardiography with indirect fick (CO₂) method of measuring cardiac output in healthy children during exercise

Paul Pianosi, Daniel Garros

Research output: Contribution to journal › Article › peer-review

35 Scopus citations

Abstract

Electric bioimpedance has been used to measure cardiac output for decades. Improvements in modeling and microprocessor technology have spawned newer generations of such devices. This method would be especially useful in children, in whom the use of invasive methods is limited. We tested a device (ICG-M401, ASK Ltd.) in 30 healthy children at 2 levels of exercise (0.5 and 1.5 W/kg), and compared impedance measurements of cardiac output (Q(ICG)) with carbon dioxide (CO₂) rebreathing measurements of cardiac output (Q(RB)). The Q(ICG)-oxygen uptake (VO₂) relation was expressed by Q(ICG) = 3.8 + 4.6 VO₂; r² = 0.68. Mean ± SD bias (Q(ICG)Q(RB)) was 0.14 ± 1.05 L/min, not significantly different from zero (95% confidence interval -0.12 to + 0.44 L/min). All Q(ICG) results were within ± 15% of the hypothetical mean value (Bland and Altman analysis). The largest deviation of Q(ICG) from Q(RB) was +30%, found in 1 of 57 paired determinations. Eighty percent of Q(ICG) values were within ±20% of the Q(RB) result. We conclude that impedance cardiography with the ICG-M401 provided realistic and reliable estimates of cardiac output in healthy children during exercise. This, along with its ease of operation and utility at rest and during exercise, make it both useful and attractive for clinic and research purposes.

Original language	English (US)
Pages (from-to)	745-749
Number of pages	5
Journal	American Journal of Cardiology
Volume	77
Issue number	9
DOIs	https://doi.org/10.1016/S0002-9149(97)89210-7
State	Published - Apr 1 1996
Externally published	Yes

Bibliographical note

Funding Information:
From the Department of Pediatrics and Child Health, Children’s Hospital of Winnipeg, and Facul of Medicine, University of Manitoba, Winnipeg, Canada. This stu fi’ y was funded by a grant from the Children’s Hospital of Winnipeg Research Foundation and the Manitoba Medical Services Foundation. Manuscript received September 22, 1995; revised manuscript received November 14, 1995, and accepted November 15. Address for reprints: Paul Pianosi, MD, CN-503, Children’s Hospital, 840 Sherbrook Street, Winnipeg, MB, Canada, R3A 1 S 1

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10.1016/S0002-9149(97)89210-7

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title = "Comparison of impedance cardiography with indirect fick (CO2) method of measuring cardiac output in healthy children during exercise",

abstract = "Electric bioimpedance has been used to measure cardiac output for decades. Improvements in modeling and microprocessor technology have spawned newer generations of such devices. This method would be especially useful in children, in whom the use of invasive methods is limited. We tested a device (ICG-M401, ASK Ltd.) in 30 healthy children at 2 levels of exercise (0.5 and 1.5 W/kg), and compared impedance measurements of cardiac output (Q(ICG)) with carbon dioxide (CO2) rebreathing measurements of cardiac output (Q(RB)). The Q(ICG)-oxygen uptake (VO2) relation was expressed by Q(ICG) = 3.8 + 4.6 VO2; r2 = 0.68. Mean ± SD bias (Q(ICG)Q(RB)) was 0.14 ± 1.05 L/min, not significantly different from zero (95% confidence interval -0.12 to + 0.44 L/min). All Q(ICG) results were within ± 15% of the hypothetical mean value (Bland and Altman analysis). The largest deviation of Q(ICG) from Q(RB) was +30%, found in 1 of 57 paired determinations. Eighty percent of Q(ICG) values were within ±20% of the Q(RB) result. We conclude that impedance cardiography with the ICG-M401 provided realistic and reliable estimates of cardiac output in healthy children during exercise. This, along with its ease of operation and utility at rest and during exercise, make it both useful and attractive for clinic and research purposes.",

author = "Paul Pianosi and Daniel Garros",

note = "Funding Information: From the Department of Pediatrics and Child Health, Children{\textquoteright}s Hospital of Winnipeg, and Facul of Medicine, University of Manitoba, Winnipeg, Canada. This stu fi{\textquoteright} y was funded by a grant from the Children{\textquoteright}s Hospital of Winnipeg Research Foundation and the Manitoba Medical Services Foundation. Manuscript received September 22, 1995; revised manuscript received November 14, 1995, and accepted November 15. Address for reprints: Paul Pianosi, MD, CN-503, Children{\textquoteright}s Hospital, 840 Sherbrook Street, Winnipeg, MB, Canada, R3A 1 S 1",

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T1 - Comparison of impedance cardiography with indirect fick (CO2) method of measuring cardiac output in healthy children during exercise

AU - Pianosi, Paul

AU - Garros, Daniel

N1 - Funding Information: From the Department of Pediatrics and Child Health, Children’s Hospital of Winnipeg, and Facul of Medicine, University of Manitoba, Winnipeg, Canada. This stu fi’ y was funded by a grant from the Children’s Hospital of Winnipeg Research Foundation and the Manitoba Medical Services Foundation. Manuscript received September 22, 1995; revised manuscript received November 14, 1995, and accepted November 15. Address for reprints: Paul Pianosi, MD, CN-503, Children’s Hospital, 840 Sherbrook Street, Winnipeg, MB, Canada, R3A 1 S 1

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N2 - Electric bioimpedance has been used to measure cardiac output for decades. Improvements in modeling and microprocessor technology have spawned newer generations of such devices. This method would be especially useful in children, in whom the use of invasive methods is limited. We tested a device (ICG-M401, ASK Ltd.) in 30 healthy children at 2 levels of exercise (0.5 and 1.5 W/kg), and compared impedance measurements of cardiac output (Q(ICG)) with carbon dioxide (CO2) rebreathing measurements of cardiac output (Q(RB)). The Q(ICG)-oxygen uptake (VO2) relation was expressed by Q(ICG) = 3.8 + 4.6 VO2; r2 = 0.68. Mean ± SD bias (Q(ICG)Q(RB)) was 0.14 ± 1.05 L/min, not significantly different from zero (95% confidence interval -0.12 to + 0.44 L/min). All Q(ICG) results were within ± 15% of the hypothetical mean value (Bland and Altman analysis). The largest deviation of Q(ICG) from Q(RB) was +30%, found in 1 of 57 paired determinations. Eighty percent of Q(ICG) values were within ±20% of the Q(RB) result. We conclude that impedance cardiography with the ICG-M401 provided realistic and reliable estimates of cardiac output in healthy children during exercise. This, along with its ease of operation and utility at rest and during exercise, make it both useful and attractive for clinic and research purposes.

AB - Electric bioimpedance has been used to measure cardiac output for decades. Improvements in modeling and microprocessor technology have spawned newer generations of such devices. This method would be especially useful in children, in whom the use of invasive methods is limited. We tested a device (ICG-M401, ASK Ltd.) in 30 healthy children at 2 levels of exercise (0.5 and 1.5 W/kg), and compared impedance measurements of cardiac output (Q(ICG)) with carbon dioxide (CO2) rebreathing measurements of cardiac output (Q(RB)). The Q(ICG)-oxygen uptake (VO2) relation was expressed by Q(ICG) = 3.8 + 4.6 VO2; r2 = 0.68. Mean ± SD bias (Q(ICG)Q(RB)) was 0.14 ± 1.05 L/min, not significantly different from zero (95% confidence interval -0.12 to + 0.44 L/min). All Q(ICG) results were within ± 15% of the hypothetical mean value (Bland and Altman analysis). The largest deviation of Q(ICG) from Q(RB) was +30%, found in 1 of 57 paired determinations. Eighty percent of Q(ICG) values were within ±20% of the Q(RB) result. We conclude that impedance cardiography with the ICG-M401 provided realistic and reliable estimates of cardiac output in healthy children during exercise. This, along with its ease of operation and utility at rest and during exercise, make it both useful and attractive for clinic and research purposes.

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