Comparative study of laparoscopic and mini-incision open donor nephrectomy: Have we heard the last word in the debate?

Kunal Yadav, Sandeep Aggarwal, Sandeep Guleria, Rajeev Kumar

Research output: Contribution to journalArticlepeer-review

5 Scopus citations


Objective: Laparoscopic donor nephrectomy (LDN) is generally considered a better option than open donor nephrectomy (ODN) as it is associated with better cosmesis, less post-operative pain and faster recovery. Mini-incision donor nephrectomy (MDN) has proven to be an effective and less invasive modification of classic ODN. Our aim was to compare the peri-operative outcomes and quality of life of donors following laparoscopic and mini-incision ODN. Methods: One hundred patients, underwent donor nephrectomy using laparoscopic approach (n = 50) or open mini-incision approach (n = 50) over a period of 18 months. Data were entered into a prospective database and analyzed retrospectively. Results: The mean operative (skin to skin) time for MDN, 53.9 min (range, 40-75 min), was significantly shorter than the 93.7 min (range, 75-140 min) for LDN. The laparoscopic donors had a longer hospital stay, warm ischemia time and higher operative and post-operative cost. There was no significant difference in the pain scores, graft function, or quality of life between the two groups. Conclusions: MDN compares well with the laparoscopic approach in terms of post-operative pain, graft function and quality of life of donors. Significantly less operative time along with the reduced cost makes it a better option in our predominantly lower BMI patient population.

Original languageEnglish (US)
Pages (from-to)328-334
Number of pages7
JournalClinical Transplantation
Issue number3
StatePublished - Mar 1 2016

Bibliographical note

Publisher Copyright:
© 2016 John Wiley & Sons A/S.


  • Laparoscopic donor nephrectomy
  • Live donor
  • Mini-incision open donor nephrectomy
  • Renal transplantation


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