Comparative DNA sequence analysis of wheat and rice genomes

Mark E. Sorells, Mauricio La Rota, Catherine E. Bermudez-Kandianis, Robert A. Greene, Ramesh Kantety, Jesse D. Munkvold, A. Miftahudin, Ahmed Mahmoud, Xuefeng Ma, Perry J. Gustafson, Lili L. Qi, Benjamin Echalier, Bikram S. Gill, David E. Matthews, Gerard R. Lazo, Shiaoman Chao, Olin D. Anderson, Hugh Edwards, Anna M. Linkiewicz, Jorge DubcovskyEduard D. Akhunov, Jan Dvorak, Deshui Zhang, Henry T. Nguyen, Junhua Peng, Nora L.V. Lapitan, Jose L. Gonzalez-Hernandez, James A. Anderson, Khwaja Hossain, Venu Kalavacharla, Shahryar F. Kianian, Dong Woog Choi, Timothy J. Close, Muharrem Dilbirligi, Kulvinder S. Gill, Camille Steber, Mary K. Walker-Simmons, Patrick E. McGuire, Calvin O. Qualset

Research output: Contribution to journalReview articlepeer-review

354 Scopus citations


The use of DNA sequence-based comparative genomics for evolutionary studies and for transferring information from model species to crop species has revolutionized molecular genetics and crop improvement strategies. This study compared 4485 expressed sequence tags (ESTs) that were physically mapped in wheat chromosome bins, to the public rice genome sequence data from 2251 ordered BAC/PAC clones using BLAST. A rice genome view of homologous wheat genome locations based on comparative sequence analysis revealed numerous chromosomal rearrangements that will significantly complicate the use of rice as a model for cross-species transfer of information in nonconserved regions.

Original languageEnglish (US)
Pages (from-to)1818-1827
Number of pages10
JournalGenome research
Issue number8
StatePublished - Aug 1 2003


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