Comparative cardiac anatomy

Alexander J. Hill, Paul A. Iaizzo

Research output: Chapter in Book/Report/Conference proceedingChapter

12 Scopus citations

Abstract

The need for appropriate animal models to conduct translational research is vital for advancements in the diagnosis and treatment of heart disease. The choice of animal model to be employed must be critically evaluated. In this chapter, we present the comparative cardiac anatomy of several of the commonly employed animal models (dog, pig, and sheep). A general comparison focuses on several specific anatomic features: the atria, the ventricles, the valves, the coronary system, lymphatics, and the conduction system. Finally, we present novel qualitative and quantitative data that we have obtained from perfusion fixed specimens of the most commonly used animal models.

Original languageEnglish (US)
Title of host publicationHandbook of Cardiac Anatomy, Physiology, and Devices
Subtitle of host publicationSecond Edition
PublisherHumana Press
Pages87-108
Number of pages22
ISBN (Print)9781588294432
DOIs
StatePublished - Dec 1 2005

Keywords

  • Cardiac
  • Comparative anatomy
  • Dog
  • Heart
  • Human
  • Pig
  • Sheep

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