TY - JOUR
T1 - Combining modular ligation and supramolecular self-assembly for the construction of star-shaped macromolecules
AU - Altintas, Ozcan
AU - Muller, Thierry
AU - Lejeune, Elise
AU - Plietzsch, Oliver
AU - Bräse, Stefan
AU - Barner-Kowollik, Christopher
PY - 2012/6/14
Y1 - 2012/6/14
N2 - A well-defined random copolymer of styrene (S) and chloromethylstyrene (CMS) featuring lateral chlorine moieties with an alkyne terminal group is prepared (P(S-co-CMS), M̄ n = 5500 Da, PDI = 1.13). The chloromethyl groups are converted into Hamilton wedge (HW) entities (P(S-co-HWS), M̄ n = 6200 Da, PDI = 1.13). The P(S-co-HWS) polymer is subsequently ligated with tetrakis(4-azidophenyl)methane to give HW-functional star-shaped macromolecules (P(S-co-HWS)) 4, M̄ n = 25 100 Da, PDI = 1.08). Supramolecular star-shaped copolymers are then prepared via self-assembly between the HW-functionalized four-arm star-shaped macromolecules (P(S-co-HW)) 4 and cyanuric acid (CA) end-functionalized PS (PS-CA, M̄ n = 3700 Da, PDI = 1.04), CA end-functionalized poly(methyl methacrylate) (PMMA-CA, M̄ n = 8500 Da, PDI = 1.13) and CA end-functionalized polyethylene glycol (PEG-CA, M̄ n = 1700 Da, PDI = 1.05). The self-assembly is monitored by 1H NMR spectroscopy and light scattering analyses.
AB - A well-defined random copolymer of styrene (S) and chloromethylstyrene (CMS) featuring lateral chlorine moieties with an alkyne terminal group is prepared (P(S-co-CMS), M̄ n = 5500 Da, PDI = 1.13). The chloromethyl groups are converted into Hamilton wedge (HW) entities (P(S-co-HWS), M̄ n = 6200 Da, PDI = 1.13). The P(S-co-HWS) polymer is subsequently ligated with tetrakis(4-azidophenyl)methane to give HW-functional star-shaped macromolecules (P(S-co-HWS)) 4, M̄ n = 25 100 Da, PDI = 1.08). Supramolecular star-shaped copolymers are then prepared via self-assembly between the HW-functionalized four-arm star-shaped macromolecules (P(S-co-HW)) 4 and cyanuric acid (CA) end-functionalized PS (PS-CA, M̄ n = 3700 Da, PDI = 1.04), CA end-functionalized poly(methyl methacrylate) (PMMA-CA, M̄ n = 8500 Da, PDI = 1.13) and CA end-functionalized polyethylene glycol (PEG-CA, M̄ n = 1700 Da, PDI = 1.05). The self-assembly is monitored by 1H NMR spectroscopy and light scattering analyses.
KW - copper-catalyzed azide-alkyne cycloaddition (CuAAC)
KW - cyanuric acid
KW - dynamic light scattering
KW - graft Hamilton wedge
KW - hydrogen bonding
KW - modular ligation
KW - nitroxide-mediated radical polymerization (NMP)
KW - self-assembly
KW - star-shaped polymer
KW - supramolecular chemistry
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U2 - 10.1002/marc.201200019
DO - 10.1002/marc.201200019
M3 - Article
C2 - 22508499
AN - SCOPUS:84861862051
VL - 33
SP - 977
EP - 983
JO - Macromolecular Rapid Communications
JF - Macromolecular Rapid Communications
SN - 1022-1336
IS - 11
ER -