Combined effect of mussel-inspired surface modification and topographical cues on the behavior of skeletal myoblasts

Sook Hee Ku, Chan Beum Park

Research output: Contribution to journalArticlepeer-review

22 Scopus citations

Abstract

The combined effect of mussel-inspired polydopamine (PDA) surface functionalization and topographical cues on the behavior of skeletal myoblasts is described. On PDA-modified nanofibers, myogenic protein expression and the fusion of myoblasts are increased significantly compared with those on unmodified nanofibers. The multinucleate myotubes on the aligned nanofibers are oriented in a direction parallel to the nanofibers.

Original languageEnglish (US)
Pages (from-to)1445-1450
Number of pages6
JournalAdvanced Healthcare Materials
Volume2
Issue number11
DOIs
StatePublished - Nov 2013

Keywords

  • Mussel adhesion
  • Myogenic differentiation
  • Nanofiber alignment
  • Polydopamine
  • Skeletal tissue engineering

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